Genomic determinants of antigen expression hierarchy in African trypanosomes.

• Tác giả: Anna Barcons-Simon, Maria Colomé-Tatché, Raúl O Cosentino, Atai Dobrynin, Zhibek Keneskhanova, Kirsty R McWilliam, Monica R Mugnier, T Nicolai Siegel, Jaclyn E Smith, Ines Subota
• Ngôn ngữ: eng
• Ký hiệu phân loại: 599.073 Collections of living mammals
• Thông tin xuất bản: England : Nature , 2025
• Bộ sưu tập: NCBI
• ID: 742288

Tóm tắt

Antigenic variation is an immune evasion strategy used by many different pathogens. It involves the periodic, non-random switch in the expression of different antigens throughout an infection. How the observed hierarchy in antigen expression is achieved has remained a mystery