Wireless recording and autoencoder denoising of intestinal activity in freely moving rats.

• Tác giả: Yuji Ikegaya, Yamato Ishii, Tetsuhiko Kashima, Nobuyoshi Matsumoto
• Ngôn ngữ: eng
• Ký hiệu phân loại: 620.11299 Engineering mechanics and materials
• Thông tin xuất bản: Japan : Journal of pharmacological sciences , 2025
• Bộ sưu tập: NCBI
• ID: 742578

Tóm tắt

Conventional wired systems for recording intestinal motility using strain-gauge transducers physically limit animal movement and are not ideal for long-term studies. Here, we developed a wireless recording system that allows continuous monitoring of intestinal activity in freely moving rats. We also developed a denoising autoencoder that isolates intestinal motility signals from locomotor noise while maintaining a 10-s temporal resolution. The refined data revealed decreased intestinal motility while the rats were behaviorally active. This system has broad applications for in vivo physiological research.