PURPOSE: Rotator cuff tear arthropathy (RCTA) is characterised by humeral head migration (HHM). The exact pathogenesis of HHM is poorly understood, although rotator cuff (RC) failure and scapular anatomy are thought to play an important role. The aim of this study is to investigate the possible association between HHM and the quantitative aspects of scapular anatomy and RC degeneration. METHODS: We analysed computed tomography scans of 43 RCTA patients. RC fatty infiltration (FI) and atrophy, HHM, and both native and pathologic scapular anatomy were quantitatively assessed in three dimensions. RESULTS: Patients with superior HHM had a significantly higher critical shoulder angle (34° vs. 30°, CONCLUSION: In RCTA, degeneration of the posterosuperior RC and acromion morphology seems to be associated with superior HHM, while in the glenoid version, the rotational alignment of the coracoacromial complex and an imbalance in FI and muscle Vol in the transverse force couple seems to be associated with anteroposterior HHM. LEVEL OF EVIDENCE: Level III.