Development of DPP-4-resistant CXCL9-Fc and CXCL10-Fc chemokines for effective cancer immunotherapy.

• Tác giả: Noor Abdala-Saleh, Dana Bar-On, Nir Berger, Ghada Jarrous, Nathan Karin, Jennie Lugassy, Gabriela Ridner-Bahar, Daniel Saidemberg, Tetsuya Taura, Abeer Turky, David Wilson
• Ngôn ngữ: eng
• Ký hiệu phân loại: 364.04 Special topics of criminology
• Thông tin xuất bản: United States : Proceedings of the National Academy of Sciences of the United States of America , 2025
• Bộ sưu tập: NCBI
• ID: 743133

Tóm tắt

CXCR3 is a chemokine receptor for three ligands: CXCL9, CXCL10, and CXCL11. Accumulating evidence, including data presented here, suggests that the interaction between CXCL9/CXCL10 and CXCR3 not only attracts CXCR3+ T cells but also promotes the induction of IFNγ-