Interleukin-6 from the adipose secretome potentiates differentiation of adipose progenitors through the activation of redox signaling.

• Tác giả: Larissa G Baker, Pina Colarusso, Antoine Dufour, Taylor B Scheidl, Jennifer A Thompson, Jessica L Wager, Sophie Z Yonan, Daniel Young
• Ngôn ngữ: eng
• Ký hiệu phân loại: 553.453 Tin
• Thông tin xuất bản: United States : American journal of physiology. Cell physiology , 2025
• Bộ sưu tập: NCBI
• ID: 743504

Tóm tắt

 Under obesogenic conditions, it is thought that a signal arising from the adipose microenvironment triggers differentiation of adipose progenitor cells (APCs)
  yet the identity and source of this signal remain unknown. Redox signaling was shown to influence adipogenesis in primary murine APCs treated with pharmacological agents to manipulate the levels of reactive oxygen species (ROS). Increased generation of superoxide ([Formula: see text]) and hydrogen peroxide (H