Always on the Move: Overview on Chromatin Dynamics within Nuclear Processes.

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Tác giả: Charlotte M Delvaux de Fenffe, Jolijn Govers, Francesca Mattiroli

Ngôn ngữ: eng

Ký hiệu phân loại: 128.46 Love

Thông tin xuất bản: United States : Biochemistry , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 743868

Our genome is organized into chromatin, a dynamic and modular structure made of nucleosomes. Chromatin organization controls access to the DNA sequence, playing a fundamental role in cell identity and function. How nucleosomes enable these processes is an active area of study. In this review, we provide an overview of chromatin dynamics, its properties, mechanisms, and functions. We highlight the diverse ways by which chromatin dynamics is controlled during transcription, DNA replication, and repair. Recent technological developments have promoted discoveries in this area, to which we provide an outlook on future research directions.
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