Exploring nightly variability and clinical influences on sleep measures: insights from a digital brain health platform.

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Tác giả: Michael L Alosco, Rhoda Au, Ileana De Anda-Duran, Huitong Ding, Kristi Ho, Phillip H Hwang, Akwaugo Igwe, Vijaya B Kolachalama, Zexu Li, Honghuang Lin, Spencer Low, Sanskruti Madan, Matthew McNulty, Jesse Mez, Zachary Popp, Salman Rahman, Edward Searls, Robert J Thomas

Ngôn ngữ: eng

Ký hiệu phân loại: 616.715 *Osteomyelitis

Thông tin xuất bản: Netherlands : Sleep medicine , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 744205

BACKGROUND: Digital technology offers a convenient way to continuously monitor sleep and assess night-to-night variability, particularly in aging populations where traditional self-reported sleep assessments may be limited. AIMS: This study aimed to investigate nightly variability in sleep measures obtained via a ring oximeter sensor in older adults and to explore the influence of demographic and cognitive factors on the stability of these metrics. METHODS: The study included 62 participants (mean age 74, 67.7 % women, 90.3 % White) from the Boston University Alzheimer's Disease Research Center (BU ADRC) cohort. Each participant wore a SleepImage Ring for at least three consecutive nights. Thirty-four continuous sleep measures, such as mean SpO2 and apnea-hypopnea index within unstable sleep, were analyzed. Night-to-night variability was assessed using intraclass correlation coefficients (ICC) based on a two-way random-effects model. Subgroup analyses examined variability by sex, age, and cognitive status. Group-level changes were assessed using one-way repeated measures ANOVA. RESULTS: Seven sleep measures demonstrated high stability across nights (ICC: 0.70-0.88), with average heart rate being the most stable, followed by mean SpO CONCLUSION: At least three nights of monitoring are required for reliable estimates of key sleep metrics. Expanding studies with larger samples and extended monitoring periods could further elucidate sleep variability as a potential non-invasive marker for general health.
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