SourceApp: A Novel Metagenomic Source Tracking Tool that can Distinguish between Fecal Microbiomes Using Genome-To-Source Associations Benchmarked Against Mixed Input Spike-In Mesocosms.

• Tác giả: Katherine E Graham, Janet K Hatt, Konstantinos T Konstantinidis, Blake G Lindner, Jacob R Phaneuf
• Ngôn ngữ: eng
• Ký hiệu phân loại: 610.28 Auxiliary techniques and procedures; apparatus, equipment, materials
• Thông tin xuất bản: United States : Environmental science & technology , 2025
• Bộ sưu tập: NCBI
• ID: 744260

Tóm tắt

Methodologies utilizing metagenomics are attractive to fecal source tracking (FST) aims for assessing the presence and proportions of various fecal inputs simultaneously. Yet, compared to established culture- or PCR-based techniques, metagenomic approaches for these purposes are rarely benchmarked or contextualized for practice. We performed shotgun sequencing experiments (