To achieve high-precision intelligent tactile recognition and hyperfine operation tasks, tactile sensors need to possess the ability to discriminate minute pressures within the range of human perception. However, due to the lack of methodologies for noise suppression, existing tactile sensing mechanisms are inferior in pressure resolution. In this work, we emulate the structure of biological fingertip Merkel cells to develop a quasi-2D vertical tunneling tactile sensor based on conformal graphene nanowalls-hexagonal boron nitride-graphene (CGNWs-hBN-Gr) van der Waals (vdWs) heterojunctions. Tunneling channel modulation of this heterojunction simulates the ion gating mechanism of piezo (PZ) proteins and greatly reduces the noise power spectral density (PSD) to 2.22 × 10