Targeting the SHOC2-RAS interaction in RAS-mutant cancers.

• Tác giả: Kim S Beyer, Jacob Brady, Elena Cavicchioli, Gregor Cremosnik, Anxhela Dhembi, Veronika Ehmke, Beatrice Faggion, Michelle Fodor, Giorgio G Galli, Daniel A Guthy, Cornelia Handl, Ulrich Hassiepen, Zachary J Hauseman, Stéphanie Katz, Grainne Kerr, Daniel A King, Mylene Lanter, Lukas Leder, Markus Linder, Sandra Lopez Romero, Danilo Maddalo, Sauveur-Michel Maira, Jean-Remy Marchand, Sandra Mollé, Zachary Nguyen, Carole Pissot Soldermann, Daniela Schildknecht, Om Shrestha, Travis Stams, Frédéric Stauffer, Claudio R Thoma, Luca Tordella, Jessica Viscomi
• Ngôn ngữ: eng
• Thông tin xuất bản: England : Nature , 2025
• Bộ sưu tập: NCBI
• ID: 745414

Tóm tắt

Activating mutations in the rat sarcoma (RAS) genes HRAS, NRAS and KRAS collectively represent the most frequent oncogenic driver in human cancer