Deletion of a novel upstream promoter of p53 impairs cold tolerance capacity in zebrafish.

• Tác giả: Xinqing Cai, Bingshe Han, Wenjuan Li, Hongkuan Song, Chang Sun, Yucheng Wang, Junfang Zhang, Ying Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 248.89425 Guides to Christian life for specific classes of persons
• Thông tin xuất bản: United States : Biochemical and biophysical research communications , 2025
• Bộ sưu tập: NCBI
• ID: 745633

Tóm tắt

P53 is a tumor suppressor that plays a crucial role in stress responses. We previously identified a novel upstream p53 promoter in cold acclimated zebrafish cells, however the functional significance of this upstream promoter under cold stress in zebrafish remains unclear. We generated novel p53 promoter