Evaluation of in vivo and in vitro binding property of a novel candidate PET tracer for CSF1R imaging and comparison with two currently-used CSF1R-PET tracers.

• Tác giả: Yuzhou Ding, Masayuki Fujinaga, Bin Ji, Jun Qian, Xiyan Rui, Chie Seki, Tomoteru Yamasaki, Ming-Rong Zhang, Nailian Zhang, Xinran Zhao, Rong Zhou
• Ngôn ngữ: eng
• Ký hiệu phân loại: 004.338 Systems analysis and design, computer architecture, performance evaluation of real-time computers
• Thông tin xuất bản: England : EJNMMI radiopharmacy and chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 745737

Tóm tắt

BACKGROUND: Colony-stimulating factor 1 receptor (CSF1R) is a promising imaging biomarker for neuroinflammation and tumor-associated macrophages. However, existing positron emission tomography (PET) tracers for CSF1R imaging often suffer from limited specificity or sensitivity. RESULTS: We have performed CONCLUSIONS: These results suggest that [