Scribble knockdown induced metastasis, identification of its associated novel molecular candidates through proteome studies.

• Tác giả: Jyotsna Singh, Saripella Srikrishna
• Ngôn ngữ: eng
• Ký hiệu phân loại: 553.3 Iron
• Thông tin xuất bản: United States : Biochemical and biophysical research communications , 2025
• Bộ sưu tập: NCBI
• ID: 745809

Tóm tắt

Metastasis is the primary cause of cancer associated deaths globally. Loss of function of Scribble, a cell polarity regulator and tumor suppressor gene, is associated with many forms of human cancers but its role in cell proliferation and metastasis remains unknown. We generated metastatic cancer condition in Drosophila using UAS