Design, synthesis and biological evaluation of novel urolithin derivatives targeting liver cancer cells.

• Tác giả: Yu Lan, Chen Li, Yipeng Ling, Mi Tian, Lirong Zhao, Benhong Zhou
• Ngôn ngữ: eng
• Ký hiệu phân loại: 149.73 Skepticism
• Thông tin xuất bản: England : Journal of enzyme inhibition and medicinal chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 746083

Tóm tắt

We designed and synthesised 22 new urolithin derivatives (UDs) based on methyl-urolithin A (mUA) to identify anti-cancer drugs with high efficacy and low toxicity and evaluated their anti-cancer activities