Blood transcriptomic associations of epigenetic age in adolescents.

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Tác giả: Anne K Bozack, Andres Cardenas, Saher Daredia, Julianna Deardorff, Brenda Eskenazi, Weihong Guo, Kim G Harley, Nina Holland, Dennis Khodasevich

Ngôn ngữ: eng

Ký hiệu phân loại: 620.107 Applied gas mechanics

Thông tin xuất bản: United States : Epigenetics , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 746114

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Epigenetic aging in early life remains poorly characterized, and patterns of gene expression can provide biologically meaningful insights. Blood DNA methylation was measured using the Illumina EPICv1.0 array and RNA sequencing was performed in blood in 174 adolescent participants (age range: 14-15 years) from the CHAMACOS cohort. Thirteen widely used epigenetic clocks were calculated, and their associations with transcriptome-wide RNA expression were tested using the

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