Oliver Wendell Holmes Sr. (1809-1894) was a poet, essayist, educator, and physician who played an important role in the formation of the American medical establishment. After studying medicine in Paris, Holmes penned what may be his most memorable satirical poem, "The Stethoscope Song," which was first published around 1848. He was a master of stethoscopy and used this ballad to reflect upon the initial resistance to its widespread adoption as well as to give a cautionary tale that auscultation should not replace a thorough medical examination. Holmes was a prominent clinician with important contributions to both medical literature and pedagogy, but he also became a notable author who set a precedent upon which future generations of physician-writers could build.