Tracking tripartite interaction dynamics: isolation, integration, and influence of bacteriophages in the

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Tác giả: Andrew Braun, Susanne DiSalvo, Andrew Hofferkamp, Negar Maness, My Tran

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Switzerland : Frontiers in microbiology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 746874

INTRODUCTION: Bacteriophages influence interactions between bacterial symbionts and their hosts by exerting parasitic pressure on symbiont populations and facilitating bacterial evolution through selection, gene exchange, and prophage integration. Host organisms also modulate phage-bacteria interactions, with host-specific contexts potentially limiting or promoting phage access to bacterial symbionts or driving alternative phenotypic or evolutionary outcomes. METHODS: To better elucidate tripartite phage-bacteria-host interactions in real-time, we expanded the RESULTS: The isolated phages exhibited diverse plaquing characteristics and virion morphologies, collectively targeting DISCUSSION: These findings highlight the variability of phage-symbiont interactions within a host environment and underscore the complex nature of phage treatment outcomes. The observed variability lays the foundation for future studies exploring the long-term dynamics of tripartite systems, suggesting potential mechanisms that may shape differential phage treatment outcomes and presenting valuable avenues for future investigation.
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