SRGN-mediated reactivation of the YAP/CRISPLD2 axis promotes aggressiveness of hepatocellular carcinoma.

• Tác giả: Yang Cao, Qiuxia Chen, Senkai Hong, Hao Hu, Wanting Hu, Bijun Huang, Weihong Kuang, Xinyu Li, Yantao Li, Zhuomao Mo, Huiting Peng, Shijun Zhang, Shuqiao Zhang, Yilu Zheng
• Ngôn ngữ: eng
• Ký hiệu phân loại: 968.8702 *Namibia, Botswana, Lesotho, Swaziland
• Thông tin xuất bản: Australia : International journal of biological sciences , 2025
• Bộ sưu tập: NCBI
• ID: 746927

Tóm tắt

Hepatocellular carcinoma (HCC) is a major contributor to global cancer-related mortality. Serglycin (SRGN) is involved in the progression of various cancers, and its overexpression is related to poor prognosis in HCC patients. Its biological role in HCC aggressiveness is unknown. This study aims to elucidate the mechanism of SRGN in HCC. Via