Leather Shaving Waste Extract as an Electrochemical Modifier at a Pencil Graphite Electrode for Paracetamol Determination in Pharmaceuticals.

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Tác giả: Wael Bosnali, Şeyma Korkmaz, Ayşen Demir Mülazımoğlu, İbrahim Ender Mülazımoğlu

Ngôn ngữ: eng

Ký hiệu phân loại: 794.147 King

Thông tin xuất bản: United States : ACS omega , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 747028

A simple, facile, and sensitive method based on leather shaving waste extract (LSWE) modified pencil graphite electrode (PGE) was developed to determine paracetamol (PAR) by employing the square wave adsorptive stripping voltammetry (SW-AdSV) technique. Leather shaving waste (LSW) was characterized by energy-dispersive X-ray spectroscopy and by investigating its morphology by taking scanning electron microscopy (SEM) images. The extraction process was conducted on an LSW by utilizing acetonitrile. Furthermore, the extraction ratio of LSW to acetonitrile was optimized and found to be 0.1 g LSW/10 mL acetonitrile at room temperature for an extraction period of 12 h. Modification of PGE by 0.1 g of LSWE (0.1LSWE/PGE) was done by performing cyclic voltammetry (CV) at the potential range 0-(+2.3) V for 10 cycles, followed by a characterization process of 0.1LSWE/PGE by employing CV, electrochemical impedance spectroscopy, and SEM techniques. PAR determination parameters at 0.1LSWE/PGE were optimized and found to be an accumulation time of 35 s in Britton Robinson buffer solution at pH 1.8. A linear relationship (
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