Synthesis and Anticancer Activity Evaluation of Novel Carborane-Containing Isoflavonoid Analogues.

• Tác giả: Guanxiang Hao, Jiali Hong, Chaofan Li, Hongjing Li, Yuzhe Lin, Kaiyan Lou, Chenyang Ma, Nan Sun, Linyuan Wang, Sinan Wang, Chengying Xie, Chuwei Yu, Changxian Yuan, Rui Zhang, Yirong Zhang, Jinhua Zhao, Lina Zhou
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : ACS omega , 2025
• Bộ sưu tập: NCBI
• ID: 747069

Tóm tắt

Isoflavonoids represent a privileged structure derived from natural products with diverse bioactivities. Carborane has been utilized as a three-dimensional mimetic of phenyl rings in medicinal chemistry. Herein, we replaced the phenyl group of isoflavonoids with carborane and prepared a series of carborane-containing isoflavonoid analogues. Compounds