OBJECTIVE: To evaluate the effect of dyadic coping-based couple psychological intervention on preoperative anxiety and postoperative pain in ectopic pregnancy patients. METHODS: A retrospective study was conducted with 100 ectopic pregnancy patients from Wuhan Children's Hospital between January 2022 and April 2024. Participants were divided into two groups: 50 in the control group (standard psychological intervention) and 50 in the observation group (dyadic coping-based psychological intervention). Outcomes were assessed using the State-Trait Anxiety Inventory (STAI), Connor-Davidson Resilience Scale (CD-RISC), Visual Analog Scale (VAS), Self-Rating Depression Scale (SDS), and Short Form-36 (SF-36). Data analysis was performed using SPSS 27.0. RESULTS: The observation group exhibited significantly higher CD-RISC and lower STAI scores (both P <
0.002) compared to the control group. SDS scores were also lower in the observation group (P = 0.044). Postoperative VAS scores and SF-36 scores (both P <
0.05) were significantly improved in the observation group at days 1, 3, and 7. Complication rates were lower in the observation group (2% vs. 18%, P = 0.008). Correlation analysis revealed higher postoperative CD-RISC scores (rho = 0.411, P <
0.002) and lower S-AI (rho = -0.297, P = 0.003), T-AI scores (rho = -0.498, P <
0.002) and SDS scores (rho = -0.217, P = 0.030) were associated with better recovery. A higher complication rate was negatively correlated with recovery (rho = -0.267, P = 0.007), while better physical functioning (PF) (rho = 0.227, P = 0.023) was positively correlated with recovery. CONCLUSION: Dyadic coping-based couple psychological intervention reduces preoperative anxiety and postoperative pain in ectopic pregnancy patients, enhances psychological resilience, and improves quality of life, fostering better health outcome and recovery.