Polymorphic variants of

• Tác giả: Mohammad Hassan Emamian, Kobra Foroughi, Akbar Fotouhi, Hassan Hashemi, Asghar Shayannia
• Ngôn ngữ: eng
• Ký hiệu phân loại: 541.2254 Theoretical chemistry
• Thông tin xuất bản: China : International journal of ophthalmology , 2025
• Bộ sưu tập: NCBI
• ID: 747163

Tóm tắt

AIM: To examine whether rs2472493 and rs248032 in the METHODS: Totally 82 POAG patients and 172 healthy controls were enrolled. The selected gene polymorphisms were analyzed using TaqMan SNP Genotyping Assay using deoxyribonucleic acid (DNA) extracted from blood samples. Allelic and genotypic frequencies were evaluated using the Chi-square test. The association between the genotypes of single nucleotide polymorphisms (SNPs) and POAG was assessed using multiple logistic regression models. The linkage disequilibrium and haplotype block structure were assessed using the Haploview 4.2 software. RESULTS: The results showed a significant association between allele frequencies of rs2472493 in the CONCLUSION: rs2472493 in the