PURPOSE OF REVIEW: High-quality evidence substantiates the use of regional anesthesia for elective total joint arthroplasty. The use of regional anesthesia in this surgical population, therefore, can also be used to evaluate health care disparities and measure health equity. This narrative review assesses and summarizes available literature on disparities in the use of regional anesthesia for total joint arthroplasty and identifies factors contributing to those disparities. RECENT FINDINGS: We found that disparities exist in the use of regional anesthesia for total joint arthroplasty and are multifactorial in origin, encompassing patient characteristics such as race and ethnicity and systemic factors such as hospital type and insurance status. However, there is an overall paucity of literature focused specifically on drivers of disparities, and no evidence supporting interventions that may alleviate known disparities. SUMMARY: Disparities in use of regional anesthesia for total joint arthroplasty are multifactorial in origin and encompass differences in care at the levels of race, ethnicity, hospital, and insurance status, among others. Additional work is needed at the epidemiologic level to understand what factors underlie known disparities in anesthesia care and how best to promote health equity for surgical patients undergoing this set of procedures.