Preoperative sarcopenia negatively impacts short- and long-term outcomes of rectal cancer: A propensity score-matched analysis.

• Tác giả: Shinya Abe, Shigenobu Emoto, Soichiro Ishihara, Kensuke Kaneko, Hiroyuki Matsuzaki, Koji Murono, Yuzo Nagai, Hiroaki Nozawa, Kazuhito Sasaki, Yuichiro Yokoyama
• Ngôn ngữ: eng
• Ký hiệu phân loại: 948.5038 *Sweden
• Thông tin xuất bản: Japan : Annals of gastroenterological surgery , 2025
• Bộ sưu tập: NCBI
• ID: 747283

Tóm tắt

 AIM: Sarcopenia is associated with poor postoperative outcomes in various cancers
  however, limited evidence is available for rectal cancer. Therefore, the present study examined the effects of skeletal muscle mass on the short- and long-term outcomes of rectal cancer. MATERIALS AND METHODS: A total of 787 Stage I-IV rectal cancer patients who underwent curative resection between 2003 and 2021 at The University of Tokyo Hospital were included. We conducted a propensity score-matched analysis to mitigate confounding bias. The third lumber psoas muscle mass was measured to define sarcopenia. RESULTS: Among 787 patients, 350 (44.5%) were classified as having sarcopenia. After matching, 532 patients were analyzed. Patient characteristics in the sarcopenia and nonsarcopenia groups were similar
  however, the body mass index differed. The sarcopenia group had significantly higher rates of postoperative complications of all grades (33.1% vs 24.8%
  CONCLUSION: Preoperative sarcopenia is associated with more total postoperative complications, more anastomotic leakage, and worse survival in rectal cancer patients.