Sex differences exist in the integrative response to exercise, however, these are typically researched during incremental and constant-load exercise. Interval exercise involves high intensity efforts interspersed with recovery periods to repeatedly stress physiological systems, and it is currently unknown whether the response to this form of exercise differs between sexes. Ten males and ten females (age: 25±3 years) completed two experimental visits. First, an incremental treadmill exercise test was performed to obtain submaximal (lactate threshold) and maximal (V̄O