Plasma Trimethylamine N-Oxide Levels in Nondialysis Chronic Kidney Disease Patients Following Meal Challenge.

• Tác giả: Natalia A Borges, Denise Mafra, Nara X Moreira, Luna Passeri, Bruna Regis, Marcelo Ribeiro-Alves
• Ngôn ngữ: eng
• Ký hiệu phân loại: 373.236 Lower level
• Thông tin xuất bản: Germany : Molecular nutrition & food research , 2025
• Bộ sưu tập: NCBI
• ID: 747836

Tóm tắt

Trimethylamine N-oxide (TMAO) is a uremic toxin accumulated in patients with chronic kidney disease (CKD) and involved with atherosclerosis. TMAO is derived from the gut microbiota (nutrient fermentation) and is found in some fish and seafood. This pilot study evaluated the acute effects of cod fish, red meat, and vegetable meal consumption on plasma TMAO levels in nondialysis CKD patients. Patients (five women, three men, 72.5 [7.7] years, body mass index [BMI], 25.6 [1.4] kg/m