Pediatric formulations in national essential medicines lists: a cross-sectional study.

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Tác giả: Bernadette Cappello, Camila Heredia, Farihah Malik, Lorenzo Moja, Martina Penazzato, Navindra Persaud, Moizza Zia Ul Haq

Ngôn ngữ: eng

Ký hiệu phân loại: 614.5992 Incidence of and public measures to prevent specific diseases and kinds of diseases

Thông tin xuất bản: Switzerland : Frontiers in pediatrics , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 748539

BACKGROUND: Children need specialized medicine formulations for proper dosing, safety, and adherence. The World Health Organization developed a pediatric essential medicines list prioritising pediatric formulations. Given global commitment by countries to children's health, we expected national lists similarly prioritizing pediatric medicines and formulations. We assessed the extent to which national lists include medicines for children. METHODS: We used a global essential medicines database to collect data on national lists identifying pediatric lists, medicines, and formulations. Six key therapeutic areas were selected RESULTS: Our study found that most countries do not include pediatric formulations in their Essential Medicine Lists (EMLs), especially high-income European countries. Of the 22 countries that do, most list medicines for infections, antiretrovirals, and cancer, but gaps exist for antitrypanosomal, antileishmanial, and antihepatitis treatments. Paracetamol had the most diverse formulations. Additionally, differences were found between national and World Health Organization (WHO) EMLs, with some countries listing fewer medicines overall, though some countries included more treatments for HIV and hepatitis than the WHO Essential Medicines List for children (EMLc). CONCLUSION: In many countries, it is unclear which medicines for children are prioritized, if any. The problem is particularly acute in high-income countries. Misalignments between national lists and the World Health Organization are common. There is little evidence that countries are adequately implementing medicines policies for youth.
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