BACKGROUND: The integration of artificial intelligence (AI) into education has the potential to revolutionize teaching and learning practices, especially in nursing education, which combines theoretical and practical knowledge. However, challenges such as infrastructural limitations, ethical considerations, and a lack of educator preparedness hinder its widespread adoption in settings with limited access to technology, insufficient funding, and inadequate training opportunities for educators. AIMS: This study explores nursing educators' perspectives on integrating AI into academic settings. METHODS: Using the Technological Pedagogical Content Knowledge framework, this qualitative study employed a phenomenological approach to understand nursing educators' lived experiences. Data were collected through 14 semistructured interviews and three focus group discussions with 16 participants from three nursing colleges in Bangladesh. Thematic analysis was conducted to identify key insights and trends. RESULTS: Nursing educators recognized the potential of AI tools, such as adaptive learning platforms, virtual simulations, and predictive analytics, to enhance teaching efficiency, personalize learning, and engage students. However, barriers such as insufficient training, infrastructural challenges, and ethical concerns related to data privacy, algorithmic bias, and AI-driven decision making were highlighted. Thematic analysis revealed five major themes: (1) perceived benefits of AI, (2) barriers to AI integration, (3) ethical considerations in AI use, (4) educator readiness and adaptation, and (5) AI as a tool for personalized learning. Many educators expressed a need for professional development and institutional support to effectively integrate AI technologies. Strategies for overcoming these challenges included targeted training programs, ethical guidelines, and addressing disparities in resource distribution. CONCLUSIONS: AI holds transformative potential for nursing education, offering opportunities to enhance teaching and learning. However, its effective integration requires addressing educators' readiness, ethical challenges, and resource limitations. These findings underscore the importance of equipping nursing educators with the necessary competencies to prepare future nurses for AI-enhanced clinical environments, thereby bridging education with evolving healthcare practice.