BACKGROUND: Artificial intelligence (AI) is significantly transforming the nursing profession, enhancing patient care, and shaping future nursing practice. Understanding nursing students' attitudes toward AI applications is crucial for its effective integration into clinical practice and education. AIM: To evaluate nursing students' attitudes toward AI in Palestine. METHODS: A cross-sectional design was conducted among 325 nursing students. Due to logistical constraints, data were gathered via online surveys using the AI attitude scale. The research was conducted between February and March 2024 at Arab American University in Palestine. RESULTS: The results showed that the average attitudes toward using AI in nursing practice scores (M = 61.81
SD = 9.74) were significantly greater than the neutral score ( CONCLUSION: Our findings demonstrate that nursing students have a positive attitude toward the integration of AI into nursing and healthcare practice, along with significant intentions to utilize the technology. The results highlight the need for AI-focused training within nursing curricula.