Distribution of PAX1 and ZNF582 Hypermethylation in the Oral Exfoliated Cells of Oral Squamous Cell Carcinoma.

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Tác giả: Ling-Fei Jia, Shuo Liu, Ya-Qing Mao, Xin Peng, Rui Sun, Guang-Yan Yu, Yao Yu, Wen-Bo Zhang

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: United States : Clinical Medicine Insights. Oncology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 748725

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BACKGROUND: The DNA methylation statuses of METHODS: Methylation data from 528 tumors and 50 adjacent nontumor tissues were acquired from The Cancer Genome Atlas and analyzed using UALCAN database. Sixty-one OSCC cases from Peking University School and Hospital of Stomatology were included in this study and the exfoliated OECs collected by oral swabs were collected from the cancerous lesion (CL), adjacent normal (AN), and contralateral normal (CN) sites. The methylation levels of these 2 genes in different sites were evaluated. CONCLUSIONS: DNA methylation detection of

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