Bladder activity of different PSMA PET radioligands and impact of furosemide.

• Tác giả: Krishna Chaudhary, Samuel Gitau, Ashesh Jani, Ismaheel Lawal, Khalid Makhdomi, Charles Marcus, Aliza Mushtaq, Manali Rupji, David Schuster, Jeffrey Switchenko
• Ngôn ngữ: eng
• Ký hiệu phân loại: 398.353 Human body, personality, qualities, activities
• Thông tin xuất bản: United States : Research square , 2025
• Bộ sưu tập: NCBI
• ID: 748796

Tóm tắt

Background Prostate-specific membrane antigen (PSMA) radioligands used for PET imaging of prostate cancer (PCa) have variable urinary excretion. The prostate bed region is an important site of disease localization where intense bladder activity may obscure lesion detection. We performed a comparative analysis of the bladder activity of different PSMA radioligands and investigated the impact of furosemide administration on bladder activity reduction. Methods This is a retrospective analysis of PSMA PET/CT images of patients with PCa who were imaged with