D3 lymph node dissection improves perioperative outcomes and overall survival in patients with cT2N0 colorectal cancer.

• Tác giả: Yinggang Chen, Yasumitsu Hirano, Bolun Song, Liming Wang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 373.236 Lower level
• Thông tin xuất bản: China : Journal of gastrointestinal oncology , 2025
• Bộ sưu tập: NCBI
• ID: 748903

Tóm tắt

BACKGROUND: The extent of lymphadenectomy undertaken in patients with cT2N0 colorectal cancer (CRC) remains controversial. The aim of our study was to compare survival in such patients by level of lymph node dissection (LND) performed. METHODS: This retrospective cohort study was conducted at a high-volume cancer center in Japan. Eligible patients (n=524) submitted to radical resections for cT2N0 CRC between April 2007 and December 2020 were included. Subjects were subsequently stratified by nature of LND (D2 RESULTS: Before matching, the D3 ( CONCLUSIONS: D3 LND improves perioperative outcomes and OS in patients with cT2N0 CRC. Accurate preoperative imaging diagnostics are critical for proper surgical management for cT2N0 CRC.