BACKGROUND: Previous studies have demonstrated an independent association between pain and frailty, but knowledge about this association with different pain characteristics is limited. OBJECTIVE: This study was embedded in a prospective, pragmatic, matched-control multicenter trial at 19 primary care practices in south-eastern Sweden (ClinicalTrials.gov 170608, ID: NCT03180606), aiming to investigate the association between frailty and pain characteristics among older people (75+) at high risk of hospitalization. METHODS: High risk of hospitalization was identified using case-finding algorithm including 32 diagnostic codes of morbidities and healthcare use. Frailty was assessed by a nurse-physician team using Clinical Frailty Scale ( RESULTS: One in three ( CONCLUSION: In older people at high risk of hospitalization, pain frequency seemed to be related to frailty, whilst ADL dependency demonstrated a stronger association.