Investigation of the DNA Methylation-Modified 8-17 DNAzyme Functions via Sensitive Catalytic Hairpin Self-Assembly Reaction.

• Tác giả: Danping Chen, Xiaofang Ding, Guoying Li, Yanqiong Liu, Haiou Ma, Yaoyao Shu, Wanxue Wang, Feng Zhang, Lang Zhang, Xinghui Zhou
• Ngôn ngữ: eng
• Ký hiệu phân loại: 496.3378 Niger-Congo languages
• Thông tin xuất bản: United States : ACS sensors , 2025
• Bộ sưu tập: NCBI
• ID: 749717

Tóm tắt

8-17 DNAzyme is a well-known versatile nucleic acid tool for achieving a specific cleavage function, and thus, investigation of 8-17 DNAzyme functions can prove to be of great significance. The conventional epigenetic modification on DNAzyme may pave a new way for the study of catalytic properties. Herein, the most abundant and best characterized modifications 5-methylcytosine (5mC) and