Vaccine Adjuvants in the Immunocompromised Host: Science, Safety, and Efficacy.

• Tác giả: Justin Z Amarin, James D Chappell, Kevin C Dee, Natasha B Halasa, Olla Hamdan, Lana Hasan, Haya Hayek, Yasmeen Z Qwaider, Wanderson Rezende
• Ngôn ngữ: eng
• Ký hiệu phân loại: 362.298 Cocaine
• Thông tin xuất bản: Denmark : Transplant infectious disease : an official journal of the Transplantation Society , 2025
• Bộ sưu tập: NCBI
• ID: 749730

Tóm tắt

Vaccine adjuvants are essential for enhancing immune responses to vaccines, particularly in immunocompromised populations who typically demonstrate suboptimal responses to standard vaccination. This narrative review evaluates the safety and efficacy of approved and candidate adjuvants in immunocompromised hosts, with emphasis on solid organ and hematopoietic cell transplant recipients. We examine conventional aluminum-based adjuvants alongside modern adjuvant systems such as AS01