Reactive nitrogen species (RNS) and reactive oxygen species (ROS) play a key role in chronic diseases and aging by initiating protein oxidation, impaired cellular membrane damage and functions, and induction of DNA mutations. When endogenous antioxidants are insufficient to counteract oxidant stress, bioactive compounds might serve as physiological therapeutic agents attributed to their ability to neutralize ROS. The aim of this study was to examine the antioxidant, chemoprotective and toxicological aspects of the hydroethanolic extract from