Intraprocedural, Intra-Arterial CT Foot Perfusion Examination for Assessment of Endovascular Therapy in Patients With Critical Limb Ischemia: A Prospective Pilot Study.

• Tác giả: Mark C Burgmans, Sivanathan Chandramohan, Apoorva Gogna, Cornelio Gutierrez, Kiang Hiong Tay, Farah Irani, Shaun X Ju Min Chan, Ankur Patel, Bien Soo Tan, Leong Sum, Thijs Urlings, Nanda Venkatanarasimah, Chow Wei Too
• Ngôn ngữ: eng
• Ký hiệu phân loại: 232.964 Burial
• Thông tin xuất bản: United States : Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists , 2025
• Bộ sưu tập: NCBI
• ID: 750372
• Chủ đề: 1. Intraprocedural; 2. Intra; 3. Arterial

Tóm tắt

BACKGROUND: Current techniques to evaluate computed tomography (CT) foot perfusion in patients with critical limb ischemia use high contrast doses and cannot be used during endovascular procedures. CT perfusion of the foot with intra-arterial contrast injection during endovascular treatment in a hybrid angiography CT suite might solve these problems. PURPOSE: The main objective of this study was to evaluate whether intra-arterial CT foot perfusion using a hybrid CT angiosystem is feasible during endovascular treatment for critical limb ischemia. MATERIAL AND METHODS: This prospective pilot study investigated intraprocedural, intra-arterial CT perfusion of the foot using a hybrid CT angiosystem in 12 patients before and after endovascular treatment for critical limb ischemia. Time to peak (TTP) and arterial blood flow were measured before and after treatment and compared using a paired RESULTS: All 24 CT perfusion maps could be calculated adequately. The contrast volume used for one perfusion CT scan was 4.8 ml. The mean TTP before treatment was 12.8 seconds (standard deviation [SD] 2.8) and the mean TTP posttreatment was 8.4 seconds (SD 1.7), this difference being statistically significant ( CONCLUSION: Computed tomography perfusion of the foot with low contrast dose intra-arterial contrast injection during endovascular treatment in a hybrid angiography CT suite is a feasible technique.Clinical ImpactIntra-arterial CT foot perfusion using a hybrid CT-angiography system is a feasible new technique during endovascular therapy for critical limb ischemia to assess the results of the treament. Future research is necessary in defining endpoints of endovascular treatment and establishing its role in limb salvage prognostication.