This study highlights the prooxidant, antiproliferative and anti-inflammatory potential of ripe Meyna spinosa Roxb. Ex Link fruit extracts. Chemical analysis by high-resolution mass spectrometry and AAS identified compounds like ursolic acid, oleanolic acid, lupeol, betulin, scopoletin, phloroglucinol and secoxyloganin and micro-elements like iron, copper, zinc and manganese. Antioxidant assays (DPPH, FRAP, metal chelation, reaction oxygen species) revealed that the M. spinosa ethyl acetate extract (MSEA) had higher phenolic (37.83 mg GAE/g DW) and flavonoid (60.22 mg QE/g DW) content, showing strong antioxidant activity (IC