Cell type-specific driver lines targeting the

• Tác giả: Nan Chen, Mark Eddison, Aljoscha Nern, Gerald M Rubin, Divya Sitaraman, Preeti Sundaramurthi, Tanya Wolff
• Ngôn ngữ: eng
• Ký hiệu phân loại: 344.0462 Labor, social service, education, cultural law
• Thông tin xuất bản: United States : bioRxiv : the preprint server for biology , 2025
• Bộ sưu tập: NCBI
• ID: 752072

Tóm tắt

The central complex (CX) plays a key role in many higher-order functions of the insect brain including navigation and activity regulation. Genetic tools for manipulating individual cell types, and knowledge of what neurotransmitters and neuromodulators they express, will be required to gain mechanistic understanding of how these functions are implemented. We generated and characterized split-GAL4 driver lines that express in individual or small subsets of about half of CX cell types. We surveyed neuropeptide and neuropeptide receptor expression in the central brain using fluorescent