Transplacental Transport Rates of Anti-Pertussis Toxin-IgG and Anti-Filamentous Hemagglutinin-IgG Antibodies in Newborns by Week of Birth.

• Tác giả: Yaprak Engin-Ustun, Mujde Can Ibanoglu, Elif Ece İnceli, Oguzhan Inceli, Cemile Sonmez, Hasan Onur Topçu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 213 Creation
• Thông tin xuất bản: United States : American journal of perinatology , 2025
• Bộ sưu tập: NCBI
• ID: 752300

Tóm tắt

The aim of this study is to investigate the lack of knowledge about the transplacental transport of antibodies in unvaccinated term and preterm infants and possible differences in antibody-mediated immunity in the fetus depending on maternal vaccination in their own infancy.The study was conducted as a prospective cross-sectional study between 2017 and 2018 and included a total of 334 participants. The study included 194 pregnant women with a preterm birth (before 37 weeks) and 140 pregnant women with a term birth. Both umbilical cord blood and maternal blood were used to measure serum levels of anti-pertussis toxin (PT) immunoglobulin (Ig) G and anti-filamentous hemagglutinin (FHA) IgG.The results showed that anti-FHA IgG antibody levels in the cord blood of women who had delivered at term were significantly higher than those of preterm infants (