OBJECTIVE: This case report demonstrates the orthodontic treatment to correct a severe scissor bite and occlusal disharmony in a 26-year-old female patient, including the use of temporary anchorage devices (TADs) and fixed orthodontic appliances. CLINICAL CONSIDERATIONS: Severe scissor bite is associated with vertical problems, such as molar extrusion. For orthodontic treatment, interradicular TADs were used to intrude the extruded molars, control the inclination of molars, correct dental midline, and improve dental relationships. CONCLUSIONS: This treatment not only achieved successful correction of the scissor bite but also provided adequate occlusion function and improved facial esthetics. CLINICAL SIGNIFICANCE: TADs provided an effective orthodontic force system to correct the scissor bite. In severe scissor bite cases, a significant amount of maxillary molar intrusion is required, which can increase the risk of moving teeth through the maxillary sinus. Using CBCT images could help in treatment planning for the three-dimensional movement of teeth during the orthodontic treatment.