Subcellular Compartmentalization of Glucose Mediated Insulin Secretion.

• Tác giả: Peter C Butler, Scott E Fraser, Tatyana Gurlo, Leslie S Satin, Zhongying Wang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 531.112 Kinematics
• Thông tin xuất bản: Switzerland : Cells , 2025
• Bộ sưu tập: NCBI
• ID: 753236

Tóm tắt

Regulation of blood glucose levels depends on the property of beta cells to couple glucose sensing with insulin secretion. This is accomplished by the concentration-dependent flux of glucose through glycolysis and oxidative phosphorylation, generating ATP. The resulting rise in cytosolic ATP/ADP inhibits K