High-Density Lipoproteins from Coronary Artery Disease and Aortic Valve Stenosis Patients Differentially Regulate Gene Expression in a Model of Cardiac Adipocytes.

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Tác giả: José Manuel Fragoso, Daniel Gómez-Pineda, Margarita Gutiérrez-Saldaña, Rebeca López-Marure, María Luna-Luna, Jonathan J Magaña, Felipe Massó, Araceli Páez, Óscar Pérez-Méndez, Zuriel Téllez-Osorio, Armando R Tovar, Ariana Vargas-Castillo, Jorge Moisés Zozaya-García

Ngôn ngữ: eng

Ký hiệu phân loại: 020.601 International organizations

Thông tin xuất bản: Switzerland : Cells , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 753244

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Previous reports have described a statistical association between high-density lipoproteins (HDL) subclasses and the expression of genes coding for pro-calcifying proteins in the epicardial adipose tissue of patients with coronary artery disease (CAD) and aortic valvular stenosis (AVS). These results suggest a causal relationship between HDL and the regulation of gene expression in epicardial adipose tissue. However, there is no experimental evidence that supports this causal relationship. Therefore, we explored the effect of HDL isolated from CAD or AVS patients on the expression of

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