BackgroundCardiovascular system is known to be affected in acromegaly. However, it was not reported to date if hemorheology was also altered and there is limited data regarding systemic oxidative status in patients with acromegaly.ObjectiveTo investigate alterations in hemorheology and systemic oxidative stress in patients with acromegaly.MethodsThe study comprised 19 active (AA) and 15 controlled (CA) acromegaly patients (n = 34, mean age 48.85 ± 1.69 years) and 29 controls (mean age 52.83 ± 1.37 years). Erythrocyte aggregation index (AI), aggregation half time (t