Uveal Melanoma in a Child: A Case Report.

• Tác giả: Ran Chen, Li Lin, Lian-di Liu, Dawei Wang, Bin Xiao, Shuang Zheng
• Ngôn ngữ: eng
• Ký hiệu phân loại: 664.72273 Grains, other seeds, their derived products
• Thông tin xuất bản: United States : Journal of clinical ultrasound : JCU , 2025
• Bộ sưu tập: NCBI
• ID: 753373

Tóm tắt

Uveal melanoma is a rare and highly malignant tumor. Its occurrence in children is rare and challenging to differentiate from retinoblastoma. The present work reports on the unusual case of a 4-year-old male patient who presented a mass in the right eye unresponsive to 18 days of ophthalmic artery chemotherapy. Enucleation revealed a solid black mass with high melanin content. The pathological diagnosis indicated uveal melanoma in the right eyeball, infiltrating the cornea and sclera. Whole-exome sequencing found no pathogenic gene variants. Further exploration of pathogenesis and molecular genetics is needed.