Clinical and Biochemical Factors Associated with Infliximab Pharmacokinetics in Paediatric Patients with Inflammatory Bowel Disease.

• Tác giả: Arno R Bourgonje, Omnia Salah Heikal, Paola Mian, Daan J Touw, Patrick F van Rheenen, Ka Yu Wang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 343.0924 Military, defense, public property, public finance, tax, commerce (trade), industrial law
• Thông tin xuất bản: Switzerland : Journal of clinical medicine , 2025
• Bộ sưu tập: NCBI
• ID: 75520

Tóm tắt

Monitoring infliximab (IFX) concentrations is crucial for optimizing IFX therapy in children with inflammatory bowel diseases (IBDs) who show low response rates due to inadequate drug exposure. Substantial variation occurs in IFX trough concentrations in paediatric patients.