The natural aging process of the human organism leads to both physiological and pathological changes, including tooth loss. This requires dental prosthetic interventions aimed at restoring patients' quality of life. The use of such prostheses necessitates selection of sufficiently strong, aesthetic and biocompatible materials, which also offer ease of shaping. The market for materials used in prosthetic applications offers a wide array of options
however, selection of the most suitable material for specific clinical scenarios can be challenging for dental professionals. This paper continues the comprehensive investigation of the physiochemical and mechanical/functional properties of two commonly used prosthetic-Biocetal and BioHPP-offering a comparative analysis of their characteristics to provide valuable insights for dentists and prosthodontists. The study focuses on in vitro analyses of physiochemical parameters, including density, water sorption, contact angle, and surface roughness. The structure of the materials was examined via scanning electron microscopy. Additionally, microbiological studies were performed using strains of