Cardiovascular diseases, particularly hypertension, pose a significant threat to global health, often referred to as a "silent killer". Traditional cuff-based blood pressure monitors have limitations in terms of convenience and continuous monitoring capabilities. As an alternative, cuffless blood pressure monitors offer a promising approach for the detection and prevention of hypertension. Despite their potential, achieving clinical performance standards remains a challenge. This review focuses on the principles of the device, current research and development, and devices that are currently approved as medical devices. Then, we describe measures to meet home and clinical performance requirements. In addition, we provide thoughts on validating the accuracy of devices in the home and hospital setting.