A Vision Transformer Model for the Prediction of Fatal Arrhythmic Events in Patients with Brugada Syndrome.

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Tác giả: Amir Averbuch, William Bertarello, Silvia Caligari, Fiorenzo Gaita, Carla Giustetto, Mira Marcus-Kalish, Eros Pasero, Vincenzo Randazzo, Andrea Saglietto, Valery Zheludev

Ngôn ngữ: eng

Ký hiệu phân loại: 636.0885 Animal husbandry

Thông tin xuất bản: Switzerland : Sensors (Basel, Switzerland) , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 79869

Brugada syndrome (BrS) is an inherited electrical cardiac disorder that is associated with a higher risk of ventricular fibrillation (VF) and sudden cardiac death (SCD) in patients without structural heart disease. The diagnosis is based on the documentation of the typical pattern in the electrocardiogram (ECG) characterized by a J-point elevation of ≥2 mm, coved-type ST-segment elevation, and negative T wave in one or more right precordial leads, called type 1 Brugada ECG. Risk stratification is particularly difficult in asymptomatic cases. Patients who have experienced documented VF are generally recommended to receive an implantable cardioverter defibrillator to lower the likelihood of sudden death due to recurrent episodes. However, for asymptomatic individuals, the most appropriate course of action remains uncertain. Accurate risk prediction is critical to avoiding premature deaths and unnecessary treatments. Due to the challenges associated with experimental research on human cardiac tissue, alternative techniques such as computational modeling and deep learning-based artificial intelligence (AI) are becoming increasingly important. This study introduces a vision transformer (ViT) model that leverages 12-lead ECG images to predict potentially fatal arrhythmic events in BrS patients. This dataset includes a total of 278 ECGs, belonging to 210 patients which have been diagnosed with Brugada syndrome, and it is split into two classes:
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