Around 8 million children with functional disabilities in India need postural support wheelchair designs. This study tests the durability and usability of a new tilt-in-space, postural support wheelchair design for children. The International Organization for Standardization (ISO) wheelchair durability testing was followed by a mixed-method observational field with a purposively selected, diverse sample of children aged 3-17 with varying diagnoses needing a tilt-in-space wheelchair in the rural and urban community settings in South India. Children were fitted with appropriate size wheelchairs. Demographic information was collected at baseline. Customized rapid surveys and interviews evaluated usability, use satisfaction, and willingness to buy and use the wheelchair device at the 2- and 12-month follow-up visits. The wheelchair passed ISO durability testing without part failures. Twelve participants (